Glaucoma is the second leading cause of blindness. The cause of glaucoma is very complicated, and some scholars believe that "autoimmune dysfunction" is also one of the mechanisms. Some researchers have suggested that allergic reactions caused by indoor and outdoor allergens will vary depending on the duration and frequency of exposure. Outdoor allergens are temporarily inhaled, so they are associated with acute diseases such as conjunctivitis and arthritis, and the principle of indoor allergy is related to chronic inflammatory diseases such as asthma.
Glaucoma is a chronic disease. It is reported that the pathophysiological processes of glaucoma are mostly inflammatory reactions. Professor Tseng of the University of California conducted a study to suggest that glaucoma patients are allergic to indoor allergens such as baboons and cats than those without glaucoma. The chances are higher, the article was published in the American Journal of Ophthalmology on February 19, 2015.
The study was a retrospective cross-sectional study involving a total of 83.3 million participants with a total incidence of 3.2% for glaucoma. Among the IgE-positive individuals, the proportion of US dust mites antigen-positive people was up to 14.5%. In the model of IgE subtype with specific allergens, there was an IgE subtype of sputum, cat, and dog antigens, and glaucoma. Significant contact. Studies have shown that antigens such as sputum and cats can increase the incidence of glaucoma, while sensitization of dog antigens reduces glaucoma.
This study showed that glaucoma patients were more likely to be allergic to indoor allergens such as sputum and cats than those without glaucoma, and further studies were needed to determine the effects of chronic indoor allergen exposure on glaucomatous optic neuropathy.